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首页  >  酶联免疫试剂盒  >  Human SERPINA3 ELISA Kit
SERPINA3 (基因名), Alpha-1-antichymotrypsin (蛋白名), AACT_HUMAN.
产品名称:

Human SERPINA3/ Alpha-1-antichymotrypsin ELISA Kit
α1抗胰糜蛋白

货号:

E1015h

商标:
EIAab®
监管等级:
别名:

ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, AACT, GIG24, GIG25

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
1.56-100umol/L
灵敏度:
0.078umol/L
特异性:
Natural and recombinant human Alpha-1-antichymotrypsin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Human SERPINA3 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤4.3%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤5.5%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

84

80-90

Plasma

86

80-92

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

91-102%

102-110%

81-91%

81-89%

EDTA plasma(n=5)

111-121%

106-116%

99-109%

87-98%

heparin plasma(n=5)

102-111%

 

83-93%

82-95%

96-106%

 

通用注释


亚单元:
Interacts with DNAJC1.


功能:
Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Alpha-1 antichymotrypsin gene signal peptide a/t polymorphism and primary intracerebral hemorrhage."

[2].
"The alanine/threonine polymorphism of the alpha-1-antichymotrypsin (SERPINA3) gene and ruptured intracranial aneurysms in the Japanese population."

[3].
"Alpha-1-antichymotrypsin (ACT or SERPINA3) polymorphism may affect age-at-onset and disease duration of Alzheimer's disease."

[4].
"A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease."

[5].
"The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity."

[6].
"Distribution of plasma alpha 1-antichymotrypsin levels in Alzheimer disease patients and controls and their genetic controls."

[7].
"A linkage disequilibrium between genes at the serine protease inhibitor gene cluster on chromosome 14q32.1 is associated with Wegener's granulomatosis."

[8].
"alpha-1-Antichymotrypsin gene A1252G variant (ACT Isehara-1) is associated with a lacunar type of ischemic cerebrovascular disease."

[9].
"Molecular studies define the primary structure of alpha1-antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of act in hippocampus and liver."

[10].
"Arginine substitutions in the hinge region of antichymotrypsin affect serpin beta-sheet rearrangement."
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