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Aaas (GeneName), Aladin (ProteinName), AAAS_MOUSE.
Product Name:

Mouse Aaas/ Aladin ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Adracalin

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Aladin
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Mouse Aaas ELISA Kit
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Mouse Aaas ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Interacts with NDC1, the interaction is required for nuclear pore localization.


Function:
Plays a role in the normal development of the peripheral and central nervous system.


Subcellular Location:
Nucleus Nuclear pore complex


This product has not yet been referenced specifically in any publications.

[1].
"Mutant WD-repeat protein in triple-A syndrome."

[2].
"The nuclear pore complex protein ALADIN is anchored via NDC1 but not via POM121 and GP210 in the nuclear envelope."

[3].
"Molecular cloning and characterization of AAAS-V2, a novel splice variant of human AAAS."

[4].
"Proteomic analysis of the mammalian nuclear pore complex."

[5].
"Triple A syndrome is caused by mutations in AAAS, a new WD-repeat protein gene."

[6].
"Triple A or Allgrove syndrome. A case report with ophthalmic abnormalities and a novel mutation in the AAAS gene."

[7].
"Tissue-specific expression and subcellular localization of ALADIN, the absence of which causes human triple A syndrome."

[8].
"The transmembrane nucleoporin NDC1 is required for targeting of ALADIN to nuclear pore complexes."

[9].
"Deficiency of ferritin heavy-chain nuclear import in triple a syndrome implies nuclear oxidative damage as the primary disease mechanism."

[10].
"A novel AAAS gene mutation (p.R194X) in a patient with triple A syndrome."
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