AADAC (GeneName), Arylacetamide deacetylase (ProteinName), AAAD_BOVIN.
Product Name:
Bovine AADAC/ Arylacetamide deacetylase ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant bovine Arylacetamide deacetylase
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
N/A
Function:
Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type II membrane protein
Microsome membrane
Single-pass type II membrane protein
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Human liver arylacetamide deacetylase. Molecular cloning of a novel esterase involved in the metabolic activation of arylamine carcinogens with high sequence similarity to hormone-sensitive lipase."
[2].
"Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis."
[3].
"Purification and characterization of a human liver arylacetamide deacetylase."
[4].
"N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity."
[5].
"Arylacetamide deacetylase: a novel host factor with important roles in the lipolysis of cellular triacylglycerol stores, VLDL assembly and HCV production."
[6].
"A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity."
[7].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
[8].
"Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency."
[9].
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."
[10].
"Human carboxylesterases and their role in xenobiotic and endobiotic metabolism."
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