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Slc7a10 (GeneName), Asc-type amino acid transporter 1 (ProteinName), AAA1_RAT.

Product Name:

Rat Slc7a10/ Asc-type amino acid transporter 1 ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

Asc-1, D-serine transporter, Solute carrier family 7 member 10, Asc1

Detection Method:

ELISA

Specificity:

Natural and recombinant rat Asc-type amino acid transporter 1

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

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Rat Slc7a10 ELISA Kit

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Product Datasheets

Data
Citations
Publication
Sequence / 3D
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General Annotation

Sub Unit:

Disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc.

Function:

Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse.

Subcellular Location:

Membrane Multi-pass membrane protein

Database link

UniGene:

Rn.128083

STRING:

10116.ENSRNOP00000015205

Pfam:

PF13520

Uniprot:

P63116

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Sequence length:

530

Sequence:

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500:

530:

YPQGSLEEEE | NGPMGQPSPL | PITDKPLKTQ |

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"Cloning and characterization of a human brain Na(+)-independent transporter for small neutral amino acids that transports D-serine with high affinity."

(PMID: 10863037)

[2].

"Is the SLC7A10 gene on chromosome 19 a candidate locus for cystinuria?"

(PMID: 11509015)

[3].

"The amino acid transporter asc-1 is not involved in cystinuria."

(PMID: 15458438)

[4].

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

(PMID: 15489334)

[5].

"Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids."

(PMID: 10734121)

[6].

"ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes."

(PMID: 25080478)

[7].

"Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development."

(PMID: 25219498)

[8].

"Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women."

(PMID: 22589738)

[9].

"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."