ADORA2A (GeneName), Adenosine receptor A2a (ProteinName), AA2AR_CANFA.
Dog ADORA2A/ Adenosine receptor A2a ELISA Kit
Natural and recombinant dog Adenosine receptor A2a
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Adenosine receptor A2a and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Interacts (via cytoplasmic C-terminal domain) with USP4; the interaction is direct (By similarity). May interact with DRD4.
Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Cell membrane Multi-pass membrane protein
MSTMGSWVYI | TVELAIAVLA | ILGNVLVCWA | VWLNSNLQNV | TNYFVVSLAA |
ADIAVGVLAI | PFAITISTGF | CAACHNCLFF | ACFVLVLTQS | SIFSLLAIAI |
DRYIAIRIPL | RYNGLVTGTR | AKGIIAVCWV | LSFAIGLTPM | LGWNNCSQPK |
EGRNYSQGCG | EGQVACLFED | VVPMNYMVYY | NFFAFVLVPL | LLMLGVYLRI |
FLAARRQLKQ | MESQPLPGER | ARSTLQKEVH | AAKSLAIIVG | LFALCWLPLH |
IINCFTFFCP | ECSHAPLWLM | YLTIVLSHTN | SVVNPFIYAY | RIREFRQTFR |
KIIRSHVLRR | REPFKAGGTS | ARALAAHGSD | GEQISLRLNG | HPPGVWANGS |
APHPERRPNG | YTLGLVSGGI | APESHGDMGL | PDVELLSHEL | KGACPESPGL |
EGPLAQDGAG | VS
This product has not yet been referenced specifically in any publications.
"Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption."
"The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist."
"Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety."
"The 1976C>T polymorphism in the adenosine A2A receptor gene does not affect the vasodilator response to adenosine in humans in vivo."
"A genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep."
"Association study of A2a adenosine receptor genetic polymorphism in panic disorder."
"Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor."
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
"Association study of 182 candidate genes in anorexia nervosa."
"Contribution of adenosine related genes to the risk of depression with disturbed sleep."
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