APP (GeneName), Amyloid beta A4 protein (ProteinName), A4_CANFA.
Product Name:
Dog APP/ Amyloid beta A4 protein ELISA Kit
Cat.#:
E0946d
Brand:
EIAab®
Regulatory Status:
Alternative:
ABPP, APP, Alzheimer disease amyloid A4 protein homolog
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.312-20ng/mL
Sensitivity:
0.115ng/mL
Specificity:
Natural and recombinant dog Amyloid beta A4 protein
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Amyloid beta A4 protein and their serial dilutions.
The results were demonstrated by the percentage of calculated concentration to the expected.
Sample | 1：2 | 1:4 | 1:8 | 1:16 |
serum(n=5) | 84-93% | 97-107% | 82-92% | 102-112% |
EDTA plasma(n=5) | 103-113% | 94-105% | 102-111% | 89-102% |
heparin plasma(n=5) | 98-110%
| 92-103% | 97-106% | 103-113% |
General Annotation
Sub Unit:
N/A
Function:
Functional neuronal receptor which couples to intracellular signaling pathway through the GTP-binding protein G(O).
Subcellular Location:
Membrane
Single-pass type I membrane protein
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP."
[2].
"Association studies testing for risk for late-onset Alzheimer's disease with common variants in the beta-amyloid precursor protein (APP)."
[3].
"Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein."
[4].
"Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid."
[5].
"Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease."
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