Serpinf2 (GeneName), Alpha-2-antiplasmin (ProteinName), A2AP_MOUSE.
Product Name:
Mouse Serpinf2/ Alpha-2-antiplasmin ELISA Kit
Cat.#:
E0160m
Brand:
EIAab®
Regulatory Status:
Alternative:
Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2, Pli
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
78-5000pg/mL
Sensitivity:
39.4pg/mL
Specificity:
Natural and recombinant mouse Alpha-2-antiplasmin
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Forms protease inhibiting heterodimer with TMPRSS7.
Function:
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
Subcellular Location:
Secreted
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"A novel missense mutation in the human plasmin inhibitor (alpha2-antiplasmin) gene associated with a bleeding tendency."
[2].
"Assignment of a single disulphide bridge in human alpha2-antiplasmin: implications for the structural and functional properties."
[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
[6].
"Association studies between the plasmin genes and late-onset Alzheimer's disease."
[7].
"Induction of alpha2-antiplasmin inhibits E-cadherin processing mediated by the plasminogen activator/plasmin system, leading to suppression of progression of oral squamous cell carcinoma via upregulation of cell-cell adhesion."
[8].
"The effect of a single nucleotide polymorphism on human alpha 2-antiplasmin activity."
[9].
"Fibrinolysis is amplified by converting alpha-antiplasmin from a plasmin inhibitor to a substrate."
[10].
"Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity."
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