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首页  >  酶联免疫试剂盒  >  Human SERPINA1 ELISA Kit
SERPINA1 (基因名), Alpha-1-antitrypsin (蛋白名), A1AT_HUMAN.
产品名称:

Human SERPINA1/ Alpha-1-antitrypsin ELISA Kit
Alpha-1-antiproteinase

货号:

E1697h

商标:
EIAab®
监管等级:
别名:

Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI, PRO0684, PRO2209

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
3.12-200ng/mL
灵敏度:
1.2ng/mL
特异性:
Natural and recombinant human Alpha-1-antitrypsin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Development Biology
Human SERPINA1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤3.7%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤5.6%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

99

93-105

Plasma

101

95-107

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

86-98%

105-114%

90-100%

100-112%

EDTA plasma(n=5)

101-114%

105-116%

89-98%

90-99%

heparin plasma(n=5)

100-112%

 

108-118%

97-108%

105-115%

 

通用注释


亚单元:
The variants S and Z interact with CANX AND PDIA3.


功能:
Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).


亚细胞位置:
Short peptide from AAT Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"Polymorphisms in the SERPINA1 (Alpha-1-Antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical therapy."

[2].
"Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study."

[3].
"Alpha-1-antitrypsin phenotypes in adult liver disease patients."

[4].
"Real time PCR detection of the PI*Z and PI*S mutations associated with alpha-1 antitrypsin deficiency."

[5].
"Prevalence of common HFE and SERPINA1 mutations in patients with hepatocellular carcinoma in a Moroccan population."

[6].
"SERPINA1 gene variants in individuals from the general population with reduced alpha1-antitrypsin concentrations."

[7].
"Isoelectric focusing phenotyping and denaturing gradient gel electrophoresis genotyping: a comparison of two methods in detection of alpha-1-antitrypsin variants."

[8].
"Determination of alpha 1-antitrypsin levels and of the presence of S and Z alleles in a population of patients with chronic respiratory symptoms."

[9].
"An alpha-1 antitrypsin genetic variant from India."

[10].
"Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients."
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