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SERPINA2 (GeneName), Putative alpha-1-antitrypsin-related protein (ProteinName), A1ATR_HUMAN.
Product Name:

Human SERPINA2/ Putative alpha-1-antitrypsin-related protein ELISA Kit

Cat.#:

E14987h

Brand:
EIAab®
Regulatory Status:
Alternative:

Protease inhibitor 1-like, Serpin A2, ARGS, ATR, PIL, SERPINA2P

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
78-5000pg/mL
Sensitivity:
38pg/ml
Specificity:
Natural and recombinant human Putative alpha-1-antitrypsin-related protein
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
Human SERPINA2 ELISA Kit
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Human SERPINA2 ELISA Kit
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Product Datasheets
Instruction: Down Instruction
MSDS: MSDS


Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤6.2%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤8.6%

Recovery
Recovery was determined by spiking various levels of Putative alpha-1-antitrypsin-related protein into serum and plasma.

Sample Type

Average(%)

Recovery Range(%)

Serum

101

95-107

Plasma

103

97-109

 

 

 

 

Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Putative alpha-1-antitrypsin-related protein and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

104-115%

104-114%

109-118%

104-115%

EDTA plasma(n=5)

97-107%

104-115%

88-97%

93-105%

heparin plasma(n=5)

84-94%

 

102-112%

99-99%

111-120%

 

General Annotation


Sub Unit:
Interacts with CANX AND PDIA3.


Function:
Putative serine protease inhibitor.


Subcellular Location:
Endoplasmic reticulum


This product has not yet been referenced specifically in any publications.

[1].
"SERPINA2 is a novel gene with a divergent function from SERPINA1."

[2].
"Sequence diversity at the proximal 14q32.1 SERPIN subcluster: evidence for natural selection favoring the pseudogenization of SERPINA2."

[3].
"A linkage disequilibrium between genes at the serine protease inhibitor gene cluster on chromosome 14q32.1 is associated with Wegener's granulomatosis."

[4].
"Update of the human and mouse SERPIN gene superfamily."

[5].
"Molecular genetics of successful smoking cessation: convergent genome-wide association study results."

[6].
"Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1."

[7].
"Molecular linkage of the human alpha 1-antitrypsin and corticosteroid-binding globulin genes on chromosome 14q32.1."

[8].
"Molecular structure and sequence homology of a gene related to alpha 1-antitrypsin in the human genome."

[9].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."

[10].
"Toward an understanding of the protein interaction network of the human liver."
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