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SCG5 (GeneName), Neuroendocrine protein 7B2 (ProteinName), 7B2_PIG.
Product Name:

Pig SCG5/ Neuroendocrine protein 7B2 ELISA Kit

Cat.#:

E9861p

Brand:
EIAab®
Regulatory Status:
Alternative:

Secretogranin V, Secretogranin-5, Secretory granule endocrine protein I, SGNE1

Detection Method:
ELISA
Specificity:
Natural and recombinant pig Neuroendocrine protein 7B2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
Pig SCG5 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.


Function:
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.


Subcellular Location:
Secreted Neuroendocrine and endocrine secretory granules.


This product has not yet been referenced specifically in any publications.
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