Pgd (GeneName), 6-phosphogluconate dehydrogenase, decarboxylating (ProteinName), 6PGD_MOUSE.
Product Name:
Mouse Pgd/ 6-phosphogluconate dehydrogenase, decarboxylating ELISA Kit
Cat.#:
E2120m
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.78-50 umol/L
Sensitivity:
0.33 umol/L
Specificity:
Natural and recombinant mouse 6-phosphogluconate dehydrogenase, decarboxylating
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homodimer.
Function:
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
Subcellular Location:
Cytoplasm
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Identification of a cDNA encoding 6-phosphogluconate dehydrogenase from a human heart cDNA library."
[2].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
[3].
"Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers."
[4].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[5].
"6-Phosphogluconate dehydrogenase: the mechanism of action investigated by a comparison of the enzyme from different species."
[6].
"Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming."
[8].
"Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis."
[9].
"TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas."
[10].
"Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase."
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