NT5C3B (GeneName), 7-methylguanosine phosphate-specific 5'-nucleotidase (ProteinName), 5NT3B_HUMAN.
Product Name:
Human NT5C3B/ 7-methylguanosine phosphate-specific 5'-nucleotidase ELISA Kit
Cat.#:
E15300h
Brand:
EIAab®
Regulatory Status:
Alternative:
7-methylguanosine nucleotidase, Cytosolic 5'-nucleotidase 3B, Cytosolic 5'-nucleotidase III-like protein, cN-III-like protein, N(7)-methylguanylate 5'-phosphatase, NT5C3L
Detection Method:
ELISA
Specificity:
Natural and recombinant human 7-methylguanosine phosphate-specific 5'-nucleotidase
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
- Feedback Wall (0)
General Annotation
Sub Unit:
Monomer.
Function:
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).
Subcellular Location:
Cytoplasm
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Crystal structures of the novel cytosolic 5'-nucleotidase IIIB explain its preference for m7GMP."
[3].
"Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses."
[5].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
[7].
"Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1."
[8].
"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
[9].
"hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes."
[10].
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
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