NT5C3B (GeneName), 7-methylguanosine phosphate-specific 5'-nucleotidase (ProteinName), 5NT3B_HUMAN.
Human NT5C3B/ 7-methylguanosine phosphate-specific 5'-nucleotidase ELISA Kit
7-methylguanosine nucleotidase, Cytosolic 5'-nucleotidase 3B, Cytosolic 5'-nucleotidase III-like protein, cN-III-like protein, N(7)-methylguanylate 5'-phosphatase, NT5C3L
Natural and recombinant human 7-methylguanosine phosphate-specific 5'-nucleotidase
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).
MAEEVSTLMK | ATVLMRQPGR | VQEIVGALRK | GGGDRLQVIS | DFDMTLSRFA |
YNGKRCPSSY | NILDNSKIIS | EECRKELTAL | LHHYYPIEID | PHRTVKEKLP |
HMVEWWTKAH | NLLCQQKIQK | FQIAQVVRES | NAMLREGYKT | FFNTLYHNNI |
PLFIFSAGIG | DILEEIIRQM | KVFHPNIHIV | SNYMDFNEDG | FLQGFKGQLI |
HTYNKNSSAC | ENSGYFQQLE | GKTNVILLGD | SIGDLTMADG | VPGVQNILKI |
GFLNDKVEER | RERYMDSYDI | VLEKDETLDV | VNGLLQHILC | QGVQLEMQGP |
This product has not yet been referenced specifically in any publications.
"Crystal structures of the novel cytosolic 5'-nucleotidase IIIB explain its preference for m7GMP."
"Identification of Drosophila and human 7-methyl GMP-specific nucleotidases."
"Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses."
"Insights into RNA biology from an atlas of mammalian mRNA-binding proteins."
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
"Initial characterization of the human central proteome."
"Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1."
"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
"hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes."
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
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