Htr7 (GeneName), 5-hydroxytryptamine receptor 7 (ProteinName), 5HT7R_RAT.
Rat Htr7/ 5-hydroxytryptamine receptor 7 ELISA Kit
5-HT-7, 5-HT-X, GPRFO, Serotonin receptor 7
Natural and recombinant rat 5-hydroxytryptamine receptor 7
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. This receptor is implicated in the regulation of mammalian circadian rhythms.
Cell membrane Multi-pass membrane protein
MMDVNSSGRP | DLYGHLRSLI | LPEVGRGLQD | LSPDGGAHPV | VSSWMPHLLS |
GFLEVTASPA | PTWDAPPDNV | SGCGEQINYG | RVEKVVIGSI | LTLITLLTIA |
GNCLVVISVC | FVKKLRQPSN | YLIVSLALAD | LSVAVAVMPF | VSVTDLIGGK |
WIFGHFFCNV | FIAMDVMCCT | ASIMTLCVIS | IDRYLGITRP | LTYPVRQNGK |
CMAKMILSVW | LLSASITLPP | LFGWAQNVND | DKVCLISQDF | GYTIYSTAVA |
FYIPMSVMLF | MYYQIYKAAR | KSAAKHKFPG | FPRVQPESVI | SLNGVVKLQK |
EVEECANLSR | LLKHERKNIS | IFKREQKAAT | TLGIIVGAFT | VCWLPFFLLS |
TARPFICGTS | CSCIPLWVER | TCLWLGYANS | LINPFIYAFF | NRDLRTTYRS |
LLQCQYRNIN | RKLSAAGMHE | ALKLAERPER | SEFVLQNSDH | CGKKGHDT
This product has not yet been referenced specifically in any publications.
"Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase."
"Molecular genetics of the platelet serotonin system in first-degree relatives of patients with autism."
"Positive association of the serotonin 5-HT7 receptor gene with schizophrenia in a Japanese population."
"Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia."
"Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization."
"Association study of the serotoninergic system in migraine in the Spanish population."
"Association study of 182 candidate genes in anorexia nervosa."
"Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?"
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
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