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Htr3b (GeneName), 5-hydroxytryptamine receptor 3B (ProteinName), 5HT3B_MOUSE.
Product Name:

Mouse Htr3b/ 5-hydroxytryptamine receptor 3B ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

5-HT3-B, Serotonin receptor 3B

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse 5-hydroxytryptamine receptor 3B
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Mouse Htr3b ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.


Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.


Subcellular Location:
Cell membrane Multi-pass membrane protein Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.


This product has not yet been referenced specifically in any publications.

[1].
"Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients."

[2].
"The 5-HT3B subunit is a major determinant of serotonin-receptor function."

[3].
"The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit."

[4].
"Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders."

[5].
"Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea."

[6].
"An association between serotonin receptor 3B gene (HTR3B) and treatment-resistant schizophrenia (TRS) in a Japanese population."

[7].
"Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine."

[8].
"Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression."

[9].
"Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists."

[10].
"Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients."
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