Htr3b (GeneName), 5-hydroxytryptamine receptor 3B (ProteinName), 5HT3B_MOUSE.
Product Name:
Mouse Htr3b/ 5-hydroxytryptamine receptor 3B ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
5-HT3-B, Serotonin receptor 3B
Detection Method:
ELISA
Specificity:
Natural and recombinant mouse 5-hydroxytryptamine receptor 3B
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.
Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Database link
This product has not yet been referenced specifically in any publications.
[1].
"Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients."
[3].
"The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit."
[4].
"Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders."
[5].
"Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea."
[6].
"An association between serotonin receptor 3B gene (HTR3B) and treatment-resistant schizophrenia (TRS) in a Japanese population."
[7].
"Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine."
[8].
"Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression."
[9].
"Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists."
[10].
"Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients."
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