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首页  >  酶联免疫试剂盒  >  Human HTR2C ELISA Kit
HTR2C (基因名), 5-hydroxytryptamine receptor 2C (蛋白名), 5HT2C_HUMAN.
产品名称:

Human HTR2C/ 5-hydroxytryptamine receptor 2C ELISA Kit
5-HT-2C

货号:

E10285h

商标:
EIAab®
监管等级:
别名:

5-HT-2C, 5-hydroxytryptamine receptor 1C, 5-HT-1C, Serotonin receptor 2C, HTR1C

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
35pg/mL
特异性:
Natural and recombinant human 5-hydroxytryptamine receptor 2C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human HTR2C ELISA Kit
规格 & 价格: cart
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Human HTR2C ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Interacts with MPDZ. Interacts with ARRB2.


功能:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.


亚细胞位置:
Cell membrane Multi-pass membrane protein


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