HTR2C (GeneName), 5-hydroxytryptamine receptor 2C (ProteinName), 5HT2C_CANFA.
Product Name:
Dog HTR2C/ 5-hydroxytryptamine receptor 2C ELISA Kit
Cat.#:
E10285d
Brand:
EIAab®
Regulatory Status:
Alternative:
5-HT-2C, 5-HT2C, 5-HTR2C, Serotonin receptor 2C
Detection Method:
ELISA
Specificity:
Natural and recombinant dog 5-hydroxytryptamine receptor 2C
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Interacts with MPDZ. Interacts with ARRB2.
Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Comorbidity between bipolar disorder and alcohol use disorder: association of dopamine and serotonin gene polymorphisms."
[2].
"A genetic variant of HTR2C may play a role in the manifestation of Tourette syndrome."
[3].
"Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder."
[4].
"Mutation screening and assessment of the effect of genetic variations on expression and RNA editing of serotonin receptor 2C in the human brain."
[5].
"Association of HTR2C, but not LEP or INSIG2, genes with antipsychotic-induced weight gain in a German sample."
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