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首页  >  酶联免疫试剂盒  >  Rat Htr2a ELISA Kit
Htr2a (基因名), 5-hydroxytryptamine receptor 2A (蛋白名), 5HT2A_RAT.
产品名称:

Rat Htr2a/ 5-hydroxytryptamine receptor 2A ELISA Kit
5-羟色胺受体2

货号:

E10283r

商标:
EIAab®
监管等级:
别名:

5-HT-2, Serotonin receptor 2A, Htr2

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.081 ng/mL
特异性:
Natural and recombinant rat 5-hydroxytryptamine receptor 2A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Rat Htr2a ELISA Kit
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Rat Htr2a ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

97-109%

108-117%

97-106%

90-100%

EDTA plasma(n=5)

95-95%

101-111%

91-101%

106-118%

heparin plasma(n=5)

103-113%

 

99-109%

80-80%

97-110%

 

通用注释


亚单元:
Interacts (via C-terminus) with MPDZ and PATJ. May interact (via C-terminus) with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2. Interacts with GRM2 and DRD2; this may affect signaling.


功能:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.


亚细胞位置:
Cell membrane Multi-pass membrane protein Cell projection Axon Cytoplasmic vesicle Membrane Caveola Cell projection Dendrite Localizes to the postsynaptic thickening of axo-dendritic synapses.


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