Home > ELISA Kit > Human HTR2A ELISA Kit

HTR2A (GeneName), 5-hydroxytryptamine receptor 2A (ProteinName), 5HT2A_HUMAN.

Product Name:

Human HTR2A/ 5-hydroxytryptamine receptor 2A ELISA Kit

Cat.#:

E10283h

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

5-HT-2, Serotonin receptor 2A, HTR2

Detection Method:

ELISA

Assay Type:

Sandwich

Detection Range:

0.156-10ng/mL

Sensitivity:

0.087ng/mL

Specificity:

Natural and recombinant human 5-hydroxytryptamine receptor 2A

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Assay Procedure:

Research Area:

Size & Price: Sign In.

Attention

Human HTR2A ELISA Kit

Email *

Message *

Please Sign In.

Product Datasheets

Instruction:

MSDS:

Data
Citations
Publication
Sequence / 3D
Feedback Wall (0)

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of 5-hydroxytryptamine receptor 2A and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	110-120%	98-108%	108-117%	107-117%
EDTA plasma(n=5)	91-101%	113-122%	105-115%	80-80%
heparin plasma(n=5)	108-117%	104-114%	89-98%	106-116%

General Annotation

Sub Unit:

Interacts (via C-terminus) with MPDZ and PATJ (PubMed:11150294, PubMed:14988405). May interact (via C-terminus) with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2 (PubMed:14988405). Interacts with GRM2 and DRD2; this may affect signaling (PubMed:18297054, PubMed:21645528, PubMed:22300836).

Function:

(Microbial infection) Acts as a receptor for human JC polyomavirus/JCPyV.

Subcellular Location:

Cell membrane Multi-pass membrane protein Cell projection Dendrite Cell projection Axon Cytoplasmic vesicle Membrane Caveola Localizes to the postsynaptic thickening of axo-dendritic synapses.

Database link

UniGene:

Hs.72630

SMR:

P28223

STRING:

9606.ENSP00000367959

KEGG:

hsa:3356

MIM:

182135

Pfam:

PF00001

Uniprot:

P28223

Related Product

Mouse Htr2a ELISA Kit

Rat Htr2a ELISA Kit

Bovine HTR2A ELISA Kit

Pig HTR2A ELISA Kit

Dog HTR2A ELISA Kit

Sequence length:

471

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

471:

QHSEEASKDN | SDGVNEKVSC | V

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"Comorbidity between bipolar disorder and alcohol use disorder: association of dopamine and serotonin gene polymorphisms."

(PMID: 20071033)

[2].

"A genetic variant of HTR2C may play a role in the manifestation of Tourette syndrome."

(PMID: 20010450)

[3].

"Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment."

(PMID: 19924111)

[4].

"Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder."

(PMID: 19095219)

[5].

"Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder."

(PMID: 19560507)

[6].

"Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study."

(PMID: 19032968)

[7].

"Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response."

(PMID: 19077664)

[8].

"HTR2A A-1438G/T102C polymorphisms predict negative symptoms performance upon aripiprazole treatment in schizophrenic patients."

(PMID: 19387614)

[9].

"Serotonin receptor 2A gene polymorphisms and schizophrenia: association with family history, diagnostic subtype and height in patients."

(PMID: 19855357)

[10].

"Analysis of serotonin receptor 2A gene (HTR2A): association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes."

(PMID: 19647026)

Feedback Wall

Displaying result : 0

All customer

Default sort

Newest first

Oldest first

No feedback yet, let's comment.