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Htr1f (GeneName), 5-hydroxytryptamine receptor 1F (ProteinName), 5HT1F_RAT.
Product Name:

Rat Htr1f/ 5-hydroxytryptamine receptor 1F ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

5-HT-1F, Serotonin receptor 1F, 5ht1f

Detection Method:
ELISA
Specificity:
Natural and recombinant rat 5-hydroxytryptamine receptor 1F
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Rat Htr1f ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
N/A


Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.


Subcellular Location:
Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase."

[2].
"Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes."

[3].
"Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships."

[4].
"Association study of the serotoninergic system in migraine in the Spanish population."

[5].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
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