Htr1f (GeneName), 5-hydroxytryptamine receptor 1F (ProteinName), 5HT1F_RAT.
Rat Htr1f/ 5-hydroxytryptamine receptor 1F ELISA Kit
5-HT-1F, Serotonin receptor 1F, 5ht1f
Natural and recombinant rat 5-hydroxytryptamine receptor 1F
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cell membrane Multi-pass membrane protein
MDFLNSSDQN | LTSEELLNRM | PSKILVSLTL | SGLALMTTTI | NCLVITAIIV |
TRKLHHPANY | LICSLAVTDF | LVAVLVMPFS | IVYIVRESWI | MGQGLCDLWL |
SVDIICCTCS | ILHLSAIALD | RYRAITDAVE | YARKRTPRHA | GITITTVWVI |
SVFISVPPLF | WRHQGNSRDD | QCIIKHDHIV | STIYSTFGAF | YIPLVLILIL |
YYKIYRAART | LYHKRQASRM | IKEELNGQVL | LESGEKSIKL | VSTSYMLEKS |
LSDPSTDFDR | IHSTVKSPRS | ELKHEKSWRR | QKISGTRERK | AATTLGLILG |
AFVICWLPFF | VKELVVNICE | KCKISEEMSN | FLAWLGYLNS | LINPLIYTIF |
NEDFKKAFQK | LVRCRN
This product has not yet been referenced specifically in any publications.
"Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase."
"Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes."
"Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships."
"Association study of the serotoninergic system in migraine in the Spanish population."
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
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