Home > ELISA Kit > Rat Htr1f ELISA Kit

Htr1f (GeneName), 5-hydroxytryptamine receptor 1F (ProteinName), 5HT1F_RAT.

Product Name:

Rat Htr1f/ 5-hydroxytryptamine receptor 1F ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

5-HT-1F, Serotonin receptor 1F, 5ht1f

Detection Method:

ELISA

Specificity:

Natural and recombinant rat 5-hydroxytryptamine receptor 1F

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

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Rat Htr1f ELISA Kit

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Product Datasheets

Data
Citations
Publication
Sequence / 3D
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General Annotation

Sub Unit:

N/A

Function:

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Database link

UniGene:

Rn.44301

STRING:

10116.ENSRNOP00000000907

Pfam:

PF00001

Uniprot:

P30940

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Sequence length:

366

Sequence:

50:

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350:

366:

NEDFKKAFQK | LVRCRN

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase."

(PMID: 8380639)

[2].

"Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes."

(PMID: 8384716)

[3].

"Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships."

(PMID: 21422162)

[4].

"Association study of the serotoninergic system in migraine in the Spanish population."

(PMID: 19455600)

[5].

"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

(PMID: 19086053)

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