HTR1E (GeneName), 5-hydroxytryptamine receptor 1E (ProteinName), 5HT1E_PIG.
Pig HTR1E/ 5-hydroxytryptamine receptor 1E ELISA Kit
5-HT-1E, Serotonin receptor 1E
Natural and recombinant pig 5-hydroxytryptamine receptor 1E
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cell membrane Multi-pass membrane protein
HQPANYLICS | LAVTDLLVAV | LVMPLSIMYI | VMDSWRLGYF | ICEVWLSVDM |
TCCTCSILHL | CVIALDRYWA | ITNAIEYARK | RTAKRAGLMI | LTVWTISIFI |
SMPPLFWRSH | RQLSPPPSQC | AIQHDHVIYT | IYSTLGAFYI | PLTLILILY
This product has not yet been referenced specifically in any publications.
"Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype."
"Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor."
"Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase."
"Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships."
"Association study of the serotoninergic system in migraine in the Spanish population."
"A common variant in DRD3 receptor is associated with autism spectrum disorder."
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
"Genetic evaluation of the serotonergic system in chronic fatigue syndrome."
"Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations."
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