HTR1E (GeneName), 5-hydroxytryptamine receptor 1E (ProteinName), 5HT1E_PIG.
Product Name:
Pig HTR1E/ 5-hydroxytryptamine receptor 1E ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
5-HT-1E, Serotonin receptor 1E
Detection Method:
ELISA
Specificity:
Natural and recombinant pig 5-hydroxytryptamine receptor 1E
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
N/A
Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype."
[2].
"Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor."
[3].
"Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase."
[4].
"Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships."
[5].
"Association study of the serotoninergic system in migraine in the Spanish population."
[6].
"A common variant in DRD3 receptor is associated with autism spectrum disorder."
[7].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
[8].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
[10].
"Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations."
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