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首页  >  酶联免疫试剂盒  >  Rat Htr1b ELISA Kit
Htr1b (基因名), 5-hydroxytryptamine receptor 1B (蛋白名), 5HT1B_RAT.
产品名称:

Rat Htr1b/ 5-hydroxytryptamine receptor 1B ELISA Kit
5 -羟色胺受体1 b

货号:

E10279r

商标:
EIAab®
监管等级:
别名:

5-HT-1B, Serotonin receptor 1B, 5ht1b

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.115ng/mL
特异性:
Natural and recombinant rat 5-hydroxytryptamine receptor 1B
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Rat Htr1b ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤3.6%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤5.6%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

99

93-105

Plasma

101

95-107

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

95-105%

93-104%

108-118%

109-120%

EDTA plasma(n=5)

105-113%

88-100%

103-113%

88-101%

heparin plasma(n=5)

106-116%

 

100-109%

106-116%

99-112%

 

通用注释


亚单元:
Homodimer. Heterodimer with HTR1D.


功能:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Lack of association between five serotonin metabolism-related genes and medication overuse headache."

[2].
"[Association study of HTR1A and HTR1B with adolescent idiopathic scoliosis]."

[3].
"Comorbidity between bipolar disorder and alcohol use disorder: association of dopamine and serotonin gene polymorphisms."

[4].
"Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder."

[5].
"Functional polymorphisms in the serotonin 1B receptor gene (HTR1B) predict self-reported anger and hostility among young men."

[6].
"SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A."

[7].
"An association study of the serotonin transporter and receptor genes with the suicidal ideation of major depression in a Chinese Han population."

[8].
"Association analysis of serotonin receptor 1B (HTR1B) and brain-derived neurotrophic factor gene polymorphisms in Borderline personality disorder."

[9].
"The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence."

[10].
"HTR1B and HTR2C in autism spectrum disorders in Brazilian families."
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