EPB41 (GeneName), Protein 4.1 (ProteinName), 41_BOVIN.
Product Name:
Bovine EPB41/ Protein 4.1 ELISA Kit
Cat.#:
E11605b
Brand:
EIAab®
Regulatory Status:
Alternative:
P4.1, 4.1R, Band 4.1, E41P
Detection Method:
ELISA
Specificity:
Natural and recombinant bovine Protein 4.1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Binds with a high affinity to glycophorin and with lower affinity to band III protein. Associates with the nuclear mitotic apparatus. Binds calmodulin and DLG1.
Function:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.
Subcellular Location:
Cytoplasm
Cytoskeleton
Cytoplasm
Cell cortex
Nucleus
This product has not yet been referenced specifically in any publications.
[1].
"An alternative domain containing a leucine-rich sequence regulates nuclear cytoplasmic localization of protein 4.1R."
[2].
"Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization."
[3].
"Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase."
[4].
"Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population."
[5].
"Marked difference in membrane-protein-binding properties of the two isoforms of protein 4.1R expressed at early and late stages of erythroid differentiation."
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