HLA-DRB1 (GeneName), HLA class II histocompatibility antigen, DRB1-1 beta chain (ProteinName), 2B11_HUMAN.
Product Name:
Human HLA-DRB1/ HLA class II histocompatibility antigen, DRB1-1 beta chain ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
MHC class II antigen DRB1*1, DR-1
Detection Method:
ELISA
Specificity:
Natural and recombinant human HLA class II histocompatibility antigen, DRB1-1 beta chain
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
(Microbial infection) Interacts with Epstein-Barr virus gp42 protein (PubMed:11864610, PubMed:9151859).
Function:
(Microbial infection) Acts as a receptor for Epstein-Barr virus on lymphocytes.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Endoplasmic reticulum membrane
Single-pass type I membrane protein
Golgi apparatus
Trans-Golgi network membrane
Single-pass type I membrane protein
Endosome membrane
Single-pass type I membrane protein
Lysosome membrane
Single-pass type I membrane protein
Late endosome membrane
Single-pass type I membrane protein
The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
This product has not yet been referenced specifically in any publications.
[2].
"Familial disease, the HLA-DRB1 shared epitope and anti-CCP antibodies influence time at appearance of substantial joint damage in rheumatoid arthritis."
[3].
"Association study of CCR5 delta 32 polymorphism among the HLA-DRB1 Caucasian population in Northern Paraná, Brazil."
[4].
"The association between the genetic polymorphism of HLA-DQA1, DQB1, and DRB1 and serum alanine aminotransferase levels in chronic hepatitis C in the Chinese population."
[5].
"Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis."
[6].
"Meta-analysis of HLA-DRB1 and HLA-DQB1 polymorphisms in Latin American patients with systemic lupus erythematosus."
[7].
"[Expression and analysis of HLA-A, B and DRB1 genes in patients with chronic myelogenous leukemia in Guangdong area]."
[8].
"Role of HLA-DRB1 and PTPN22 genes in susceptibility to juvenile idiopathic arthritis in Hungarian patients."
[10].
"Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis."
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