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HLA-DRB1 (GeneName), HLA class II histocompatibility antigen, DRB1-1 beta chain (ProteinName), 2B11_HUMAN.

Product Name:

Human HLA-DRB1/ HLA class II histocompatibility antigen, DRB1-1 beta chain ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

MHC class II antigen DRB1*1, DR-1

Detection Method:

ELISA

Specificity:

Natural and recombinant human HLA class II histocompatibility antigen, DRB1-1 beta chain

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

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Human HLA-DRB1 ELISA Kit

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Product Datasheets

Data
Citations
Publication
Sequence / 3D
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General Annotation

Sub Unit:

(Microbial infection) Interacts with Epstein-Barr virus gp42 protein (PubMed:11864610, PubMed:9151859).

Function:

(Microbial infection) Acts as a receptor for Epstein-Barr virus on lymphocytes.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Endoplasmic reticulum membrane Single-pass type I membrane protein Golgi apparatus Trans-Golgi network membrane Single-pass type I membrane protein Endosome membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Late endosome membrane Single-pass type I membrane protein The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.

Database link

UniGene:

Hs.534322

SMR:

P04229

MIM:

142857

Pfam:

PF07654

Uniprot:

P04229

Related Product

Human HLA-DRB1 CLIA Kit

Human HLA-DRB1 Protein

Human HLA-DRB1 Polyclonal Antibody

Sequence length:

266

Sequence:

50:

100:

150:

200:

250:

266:

RNQKGHSGLQ | PTGFLS

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"MICA polymorphisms and haplotypes with HLA-B and HLA-DRB1 in Koreans."

(PMID: 19895570)

[2].

"Familial disease, the HLA-DRB1 shared epitope and anti-CCP antibodies influence time at appearance of substantial joint damage in rheumatoid arthritis."

(PMID: 19117726)

[3].

"Association study of CCR5 delta 32 polymorphism among the HLA-DRB1 Caucasian population in Northern Paraná, Brazil."

(PMID: 18623133)

[4].

"The association between the genetic polymorphism of HLA-DQA1, DQB1, and DRB1 and serum alanine aminotransferase levels in chronic hepatitis C in the Chinese population."

(PMID: 18028350)

[5].

"Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis."

(PMID: 18952831)

[6].

"Meta-analysis of HLA-DRB1 and HLA-DQB1 polymorphisms in Latin American patients with systemic lupus erythematosus."

(PMID: 18295738)

[7].

"[Expression and analysis of HLA-A, B and DRB1 genes in patients with chronic myelogenous leukemia in Guangdong area]."

(PMID: 18718089)

[8].

"Role of HLA-DRB1 and PTPN22 genes in susceptibility to juvenile idiopathic arthritis in Hungarian patients."

(PMID: 19210888)

[9].

"Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis."

(PMID: 18832704)

[10].

"Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis."

(PMID: 18240242)

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