Ppp2r5b (GeneName), Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (ProteinName), 2A5B_RAT.
Product Name:
Rat Ppp2r5b/ Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
PP2A B subunit isoform B'-beta,PP2A B subunit isoform B56-beta,PP2A B subunit isoform PR61-beta,PP2A B subunit isoform R5-beta,LOC100909468,rCG_47223
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Product Overview:
is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay)
Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform) ELISA Kit target analytes in biological samples. The concentration gradients of
the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform. The ELISA analytical biochemical
technique of the kit is based on Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody-Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform. Appropriate sample types may include undiluted human body fluids
and/or tissue homogenates,
secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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General Annotation
Sub Unit:
Component of the serine/threonine-protein phosphatase 2A complex (PP2A). This complex consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant scaffold subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with SGO1. Interacts with AKT1.
Function:
As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.
Subcellular Location:
Cytoplasm
Database links
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Vaild Sequence:
This product has not yet been referenced specifically in any publications.
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