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Ppp2r5b (GeneName), Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (ProteinName), 2A5B_RAT.
Product Name:

Rat Ppp2r5b/ Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

PP2A B subunit isoform B'-beta, PP2A B subunit isoform B56-beta, PP2A B subunit isoform PR61-beta, PP2A B subunit isoform R5-beta, LOC100909468, rCG_47223

Detection Method:
ELISA
Specificity:
Natural and recombinant rat Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Rat Ppp2r5b ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Component of the serine/threonine-protein phosphatase 2A complex (PP2A). This complex consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant scaffold subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with SGO1. Interacts with AKT1.


Function:
As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.


Subcellular Location:
Cytoplasm


This product has not yet been referenced specifically in any publications.
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