Ppp2r5a (GeneName), Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (ProteinName), 2A5A_MOUSE.
Product Name:
Mouse Ppp2r5a/ Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PR61alpha, PP2A B subunit isoform R5-alpha
Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Sequence / 3D
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General Annotation
Sub Unit:
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with SGO1.
Function:
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Subcellular Location:
Cytoplasm
Nucleus
Chromosome
Centromere
From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase (By similarity).
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
This product has not yet been referenced specifically in any publications.
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