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Ppp2r5a (GeneName), Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (ProteinName), 2A5A_MOUSE.

Product Name:

Mouse Ppp2r5a/ Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PR61alpha, PP2A B subunit isoform R5-alpha

Detection Method:

ELISA

Specificity:

Natural and recombinant mouse Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

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Mouse Ppp2r5a ELISA Kit

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Product Datasheets

Data
Citations
Sequence / 3D
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General Annotation

Sub Unit:

PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with SGO1.

Function:

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Subcellular Location:

Cytoplasm Nucleus Chromosome Centromere From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase (By similarity).

Database link

UniGene:

Mm.205569

SMR:

Q6PD03

STRING:

10090.ENSMUSP00000070726

KEGG:

mmu:226849

Pfam:

PF01603

Uniprot: