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YWHAG (GeneName), 14-3-3 protein gamma (ProteinName), 1433G_BOVIN.
Product Name:

Bovine YWHAG/ 14-3-3 protein gamma ELISA Kit

 
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Protein kinase C inhibitor protein 1,KCIP-1

Detection Method:
ELISA
Specificity:
Natural and recombinant bovine 14-3-3 protein gamma
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Cancer
Product Overview:
is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (14-3-3 protein gamma) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing 14-3-3 protein gamma. The ELISA analytical biochemical technique of the kit is based on 14-3-3 protein gamma antibody-14-3-3 protein gamma antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect 14-3-3 protein gamma antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, 14-3-3 protein gamma. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Bovine YWHAG ELISA Kit
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Product Datasheets
Datasheet:


General Annotation


Sub Unit:
Homodimer. Interacts with MDM4 (phosphorylated); negatively regulates MDM4 activity toward TP53. Interacts with RAF1, SSH1 and CRTC2/TORC2. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with GAB2 and SAMSN1. Interacts with PKA-phosphorylated AANAT and SIRT2 (By similarity). Interacts with the 'Thr-369' phosphorylated form of DAPK2 (By similarity). Interacts with PI4KB, TBC1D22A and TBC1D22B (By similarity). Interacts with SLITRK1.


Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.


Subcellular Location:
Cytoplasm


This product has not yet been referenced specifically in any publications.
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[1].
"Cloning, expression, and chromosomal mapping of the human 14-3-3gamma gene (YWHAG) to 7q11.23."

[2].
"14-3-3Gamma interacts with and is phosphorylated by multiple protein kinase C isoforms in PDGF-stimulated human vascular smooth muscle cells."

[3].
"De Novo Mutations in YWHAG Cause Early-Onset Epilepsy."

[4].
"ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding."

[5].
"Centrosome-related genes, genetic variation, and risk of breast cancer."

[6].
"Genome-wide association study of severity in multiple sclerosis."

[7].
"SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner."

[8].
"Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein."

[9].
"Reduced expression of 14-3-3 gamma in uterine leiomyoma as identified by proteomics."

[10].
"14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation."
Sample Data
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