027-59234612(+86)
EIAab
Home  >  ELISA Kit  >  Human YWHAH ELISA Kit
YWHAH (GeneName), 14-3-3 protein eta (ProteinName), 1433F_HUMAN.
Product Name:

Human YWHAH/ 14-3-3 protein eta ELISA Kit

Cat.#:

E14292h

Brand:
EIAab®
Regulatory Status:
Alternative:

Protein AS1, YWHA1

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.78-50ng/mL
Sensitivity:
0.365ng/mL
Specificity:
Natural and recombinant human 14-3-3 protein eta
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
Cancer
Human YWHAH ELISA Kit
Size & Price: Sign In.
×
Human YWHAH ELISA Kit
Email *
Message *
Please Sign In.
Product Datasheets
Instruction: Down Instruction
MSDS: MSDS


General Annotation


Sub Unit:
Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with ARHGEF28 and CDK16 (By similarity). Weakly interacts with CDKN1B. Interacts with GAB2. Interacts with KCNK18 in a phosphorylation-dependent manner. Interacts with SAMSN1 (By similarity). Interacts with the 'Ser-241' phosphorylated form of PDPK1. Interacts with the 'Thr-369' phosphorylated form of DAPK2 (PubMed:26047703). Interacts with PI4KB, TBC1D22A and TBC1D22B (PubMed:23572552). Interacts with SLITRK1 (PubMed:19640509).


Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.

[1].
"Systematic screening of the 14-3-3 eta (eta) chain gene for polymorphic variants and case-control analysis in schizophrenia."

[2].
"14-3-3 protein eta chain gene (YWHAH) polymorphism and its genetic association with schizophrenia."

[3].
"The human and bovine 14-3-3 eta protein mRNAs are highly conserved in both their translated and untranslated regions."

[4].
"cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain."

[5].
"ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding."

[6].
"Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study."

[7].
"Family-based association of YWHAH in psychotic bipolar disorder."

[8].
"SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner."

[9].
"Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein."

[10].
"Structural basis for protein-protein interactions in the 14-3-3 protein family."
Close
Sample Data
Close
Sample Data
Close
Sample Data
My Cart close
Attention close
History close
Clear All
Comparison close
User
My Cart
Attention
History
Comparison
Top
Message
close_message
Product Name *
Email *
Message: *
Inform
new Message
Size Quantity Price ($) Subtotal 1 ($)
Subtotal 2: $
triangle
Size Quantity Price ($)
Do you want to be our agent and get a lower discount?
Please contact us:
Tel:027-59234612(+86)
Fax:027-59759960(+86)
Email:sales@eiaab.com