NMU (GeneName), Neuromedin-U (ProteinName), 10703_EIAAB.
Human NMU/ Neuromedin-U ELISA Kit
Natural and recombinant human Neuromedin-U
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.
MLRTESCRPR | SPAGQVAAAS | PLLLLLLLLA | WCAGACRGAP | ILPQGLQPEQ |
QLQLWNEIDD | TCSSFLSIDS | QPQASNALEE | LCFMIMGMLP | KPQEQDEKDN |
TKRFLFHYSK | TQKLGKSNVV | SSVVHPLLQL | VPHLHERRMK | RFRVDEEFQS |
PFASQSRGYF | LFRPRNGRRS | AGFI
This product has not yet been referenced specifically in any publications.
"Cloning and characterization of the cDNA encoding the human neuromedin U (NmU) precursor: NmU expression in the human gastrointestinal tract."
"Association between neuromedin U gene variants and overweight and obesity."
"Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals."
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
"Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathway."
"Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S."
"Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia."
"The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer."
"Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias."
"Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction."
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