GABA (Shorten Name ),
Product Name:
General GABA/ Gamma-Aminobutyric acid ELISA Kit
Cat.#:
E0900Ge
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
1.56-100ng/mL
Sensitivity:
0.45ng/mL
Specificity:
Natural and recombinant general Gamma-Aminobutyric acid
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
-
- Data
- Citations ( 12 )
- Sequence / 3D
- Feedback Wall (0)
Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Gamma-Aminobutyric acid and their serial dilutions.
The results were demonstrated by the percentage of calculated concentration to the expected.
|
Sample |
1：2 |
1:4 |
1:8 |
1:16 |
|
serum(n=5) |
104-114% |
83-93% |
94-103% |
86-96% |
|
EDTA plasma(n=5) |
102-113% |
81-93% |
102-112% |
90-102% |
|
heparin plasma(n=5) |
106-116%
|
80-93% |
92-101% |
96-104% |
General Annotation
Sub Unit:
N/A
Function:
γ-Aminobutyric acid is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone.
Although chemically it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, conventionally refers to the alpha amino acids, which GABA is not, nor is it ever incorporated into a protein.
In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition's upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.
Location:
N/A
Valid Sequence:
[2].
[3].
Mona M. A, Mohamed M.A. H.
[4].
H N. Shalaby, D M. EI-Tanbouly, H F. Zaki.
[6].
N N. Shahin, M M. Safar, S M. Rizk, et al.
[9].
Maha H. D, Manar E. S, Yasmina M. A, et al.
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