CTXII (Shorten Name ),
Product Name:
Rat CTXII/ C-telopeptide of Collagen alpha-1(II) chain ELISA Kit
Cat.#:
E0686r
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
78-5000pg/ml
Sensitivity:
39pg/mL
Specificity:
Natural and recombinant rat C-telopeptide of Collagen alpha-1(II) chain
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:

Research Area:
-
- Data
- Citations
- Sequence / 3D
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Precision
Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤6.5%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤9.3%
Recovery
Recovery was determined by spiking various levels of C-telopeptide of Collagen alpha-1(II) chain into serum and plasma.
Sample Type |
Average(%) |
Recovery Range(%) |
Serum |
101 |
95-107 |
Plasma |
103 |
97-109 |
Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of C-telopeptide of Collagen alpha-1(II) chain and their serial dilutions.
The results were demonstrated by the percentage of calculated concentration to the expected.
Sample |
1:2 |
1:4 |
1:8 |
1:16 |
serum(n=5) |
109-119% |
110-120% |
90-100% |
94-103% |
EDTA plasma(n=5) |
92-102% |
103-114% |
98-107% |
102-110% |
heparin plasma(n=5) |
107-116%
|
100-110% |
95-105% |
110-120% |
General Annotation
Sub Unit:
N/A
Function:
In bone physiology, the C-terminal telopeptide (or more formally, carboxy-terminal collagen crosslinks, and known by the acronym CTX) is a serum biomarker used to measure the rate of bone turnover. It can be useful in assisting clinicians to determine a patient's nonsurgical treatment response as well as evaluate a patient's risk of developing complications during healing following surgical intervention. The test used to detect the CTX marker is called the Serum CrossLaps, and it is more specific to bone resorption than any other test currently available.
Location:
N/A
This product has not yet been referenced specifically in any publications.
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