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LAM (Shorten Name ),
Product Name:

General LAM/ Lipoarabinomannan ELISA Kit

Cat.#:

E1544Ge

Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
0.312-20ng/mL
Sensitivity:
0.101ng/mL
Specificity:
Natural and recombinant general Lipoarabinomannan
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
General LAM ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Lipoarabinomannan and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

85-95%

103-113%

91-102%

109-118%

EDTA plasma(n=5)

91-101%

95-104%

96-105%

102-112%

heparin plasma(n=5)

102-114%

 

84-94%

103-113%

105-118%

 

General Annotation


Sub Unit:
Lipoarabinomannan is synthesized when a mannopyranosyl adds to a phosphoinositol to produce PIMs and lipomannan(LM). PIM and LM are then glycosylated with arabinan to form LAM.


Function:
Lipoarabinomannan, also called LAM, is a glycolipid, and a virulence factor associated with Mycobacterium tuberculosis, the bacteria responsible for tuberculosis. Its primary function is to inactivate macrophages and scavenge oxidative radicals.


Location:
N/A


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