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DPD (Shorten Name ),
Product Name:

General DPD/ Deoxypyridinoline ELISA Kit

Cat.#:

E0894Ge

Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
1.56-100ng/mL
Sensitivity:
0.47ng/mL
Specificity:
Natural and recombinant general Deoxypyridinoline
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
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General DPD ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Deoxypyridinoline and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

100-110%

108-118%

89-99%

102-112%

EDTA plasma(n=5)

101-111%

93-104%

92-103%

86-94%

heparin plasma(n=5)

94-102%

 

107-117%

97-107%

103-112%

 

General Annotation


Sub Unit:
N/A


Function:
Deoxypyridinoline, also called D-Pyrilinks, Pyrilinks-D, or deoxyPYD, is one of two pyridinium cross-links that provide structural stiffness to type I collagen found in bones. It is excreted unmetabolized in urine and is a specific marker of bone resorption and osteoclastic activity. It is measured in urine tests and is used along with other bone markers such as alkaline phosphatase, osteocalcin, and N-terminal telopeptide to diagnose bone diseases such as postmenopausal osteoporosis, bone metastasis, and Paget's disease, furthermore, it has been useful in monitoring treatments that conatin bone-active agents such as estrogens and bisphosphonates.


Location:
N/A


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