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MMA (Shorten Name ),
Product Name:

General MMA/ Methylmalonic Acid ELISA Kit

Cat.#:

E2091Ge

Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
0.312-20ng/mL
Sensitivity:
0.099ng/mL
Specificity:
Natural and recombinant general Methylmalonic Acid
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
General MMA ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Methylmalonic Acid and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

102-112%

81-91%

102-111%

111-120%

EDTA plasma(n=5)

97-110%

102-113%

105-115%

86-96%

heparin plasma(n=5)

105-116%

 

110-120%

104-115%

105-115%

 

General Annotation


Sub Unit:
N/A


Function:
Methylmalonic acid (MMA) is a dicarboxylic acid that is a C-methylated derivative of malonate. The coenzyme A linked form of methylmalonic acid, methylmalonyl-CoA, is converted into succinyl-CoA by methylmalonyl-CoA mutase, in a reaction that requires vitamin B12 as a cofactor. In this way, it enters the Krebs cycle, and is thus part of one of the anaplerotic reactions.


Location:
N/A


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