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NA (Shorten Name ),
Product Name:

General NA/ Noradrenaline ELISA Kit

Cat.#:

E0907Ge

Brand:
EIAab®
Regulatory Status:
Alternative:

NE, Norepinephrine, Isoprenaline

Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
31.2-2000pg/mL
Sensitivity:
9.8pg/mL
Specificity:
Natural and recombinant general Noradrenaline
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
General NA ELISA Kit
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General NA ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Noradrenaline and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

82-92%

80-90%

86-96%

98-108%

EDTA plasma(n=5)

90-103%

110-118%

98-110%

84-96%

heparin plasma(n=5)

84-94%

 

87-97%

92-101%

104-114%

 

General Annotation


Sub Unit:
N/A


Function:
One of the most important functions of Noradrenaline is its role as the neurotransmitter released from the sympathetic neurons affecting the heart. An increase in Noradrenaline from the sympathetic nervous system increases the rate of contractions. When Noradrenaline acts as a drug, it increases blood pressure by increasing vascular tone (tension of vascular smooth muscle) through α-adrenergic receptor activation; a reflex bradycardia homeostatic baroreflex is overcome by a compensatory reflex preventing an otherwise inevitable drop in heart rate to maintain blood pressure.


Location:
Noradrenaline is synthesized from dopamine by dopamine β-hydroxylase.[8] It is released from the adrenal medulla into the blood as a hormone, and is also a neurotransmitter in the central nervous system and sympathetic nervous system, where it is released from noradrenergic neurons in the locus coeruleus. The actions of norepinephrine are carried out via the binding to adrenergic receptors.


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