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ALD (Shorten Name ),
Product Name:

General ALD/ Aldosterone ELISA Kit

Cat.#:

E0911Ge

Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
0.39-25ng/mL
Sensitivity:
0.194ng/mL
Specificity:
Natural and recombinant general Aldosterone
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
General ALD ELISA Kit
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General ALD ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Aldosterone and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

101-112%

111-121%

88-99%

81-90%

EDTA plasma(n=5)

89-102%

107-117%

107-119%

105-115%

heparin plasma(n=5)

105-116%

 

101-112%

105-117%

116-126%

 

General Annotation


Sub Unit:
N/A


Function:
Aldosterone is a yellow steroid hormone (mineralocorticoid family) produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts mainly on the distal tubules and collecting ducts of the nephron, the functioning unit of the kidney, to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney -- increasing blood volume and, therefore, increasing blood pressure.


Location:
Steroid receptors are intracellular. The aldosterone mineralcorticoid receptor (MR) complex binds on the DNA to specific hormone response element, which leads to gene specific transcription.


This product has not yet been referenced specifically in any publications.
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