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MDA (Shorten Name ),
Product Name:

General MDA/ Malondialdehyde ELISA Kit

Cat.#:

E0597Ge

Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
0.312-20nmol/mL
Sensitivity:
0.088nmol/mL
Specificity:
Natural and recombinant general Malondialdehyde
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
General MDA ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Malondialdehyde and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

108-116%

95-107%

105-115%

94-104%

EDTA plasma(n=5)

106-118%

103-113%

81-93%

98-98%

heparin plasma(n=5)

99-111%

 

107-117%

101-111%

98-108%

 

General Annotation


Sub Unit:
N/A


Function:
Malondialdehyde reacts with deoxyadenosine and deoxyguanosine in DNA, forming DNA adducts, the primary one being M1G, which is mutagenic. The guanidine group of arginine residues condense with MDA to give 2-aminopyrimidines.


Location:
Malondialdehyde is the organic compound with the formula CH2(CHO)2. The structure of this species is more complex than this formula suggests. This reactive species occurs naturally and is a marker for oxidative stress.


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