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17OHP (短名 ),
产品名称:

General 17OHP/ 17-Hydroxyprogesterone ELISA Kit
17-羟孕酮

货号:

E0454Ge

商标:
EIAab®
监管等级:
别名:

17-OH progesterone

检测方法:
ELISA
实验类型:
Competitive
检测范围:
31.2-2000pg/mL
灵敏度:
10.2pg/mL
特异性:
Natural and recombinant general 17-Hydroxyprogesterone
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
General 17OHP ELISA Kit
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General 17OHP ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤5.7%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤7.9%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

97

91-103

Plasma

99

93-105

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

84-95%

107-116%

101-110%

97-107%

EDTA plasma(n=5)

95-104%

107-116%

91-103%

106-116%

heparin plasma(n=5)

96-105%

 

91-100%

107-117%

110-120%

 

通用注释


亚单元:
N/A


功能:
17-Hydroxyprogesterone (17-OH progesterone or 17OHP) is a C-21 steroid hormone produced during the synthesis of glucocorticoids and sex steroids. As a hormone, 17OHP also interacts with the progesterone receptor.


Location:
Measurements of levels of 17-hydroxyprogesterone are useful in the evaluation of patients with suspected congenital adrenal hyperplasia as the typical enzymes that are defective, namely 21-hydroxylase and 11β-hydroxylase, lead to a build-up of 17OHP. In contrast, the rare patient with 17α-hydroxylase deficiency will have very low or undetectable levels of 17OHP. 17OHP levels can also be used to measure contribution of progestational activity of the corpus luteum during pregnancy as progesterone but not 17OHP is also contributed by the placenta.


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