T3 (Shorten Name ),
General T3/ Triiodothyronine ELISA Kit
Natural and recombinant general Triiodothyronine
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Triiodothyronine and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Triiodothyronine, C15H12I3NO4, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
The T3 (and T4) bind to nuclear receptors, thyroid receptors. T3 (and T4) are very lipophilic and able to pass through the phospholipid bilayers of target cells. The lipophilicity of T3 (and T4) requires their binding to the protein carrier thyroid-binding protein (TBG) [thyroxine-binding globulins, thyroxine binding prealbumins, and albumins] for transport in the blood. The thyroid receptors bind to response elements in gene promoters, thus enabling them to activate or inhibit transcription. The sensitivity of a tissue to T3 is modulated through the thyroid receptors.
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From: Environmental Pollution
"Embryonic exposure to soil samples from a gangue stacking area induces thyroid hormone disruption in zebrafish"
Fl Yang, Gk Li, N Sang.
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