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T3 (Shorten Name ),
Product Name:

General T3/ Triiodothyronine ELISA Kit

Cat.#:

E0453Ge

Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
78-5000pg/mL
Sensitivity:
35pg/mL
Specificity:
Natural and recombinant general Triiodothyronine
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
General T3 ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Triiodothyronine and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

87-97%

92-100%

95-104%

80-91%

EDTA plasma(n=5)

106-114%

103-112%

90-100%

86-95%

heparin plasma(n=5)

110-119%

 

104-114%

81-91%

90-100%

 

General Annotation


Sub Unit:
N/A


Function:
Triiodothyronine, C15H12I3NO4, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.


Location:
The T3 (and T4) bind to nuclear receptors, thyroid receptors. T3 (and T4) are very lipophilic and able to pass through the phospholipid bilayers of target cells. The lipophilicity of T3 (and T4) requires their binding to the protein carrier thyroid-binding protein (TBG) [thyroxine-binding globulins, thyroxine binding prealbumins, and albumins] for transport in the blood. The thyroid receptors bind to response elements in gene promoters, thus enabling them to activate or inhibit transcription. The sensitivity of a tissue to T3 is modulated through the thyroid receptors.



[2].
Suyoung Kim, Kyunghee Ji, Sangwoo Lee, Jinyoung Lee, Jungkon Kim, Sunmi Kim, Younglim Kho, Kyungho Choi

[9].
A. Chabowski, M. Żendzian-Piotrowska, A. Mikłosz, et al.
From: Lipids
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