ADAM12 (基因名), Disintegrin and metalloproteinase domain-containing protein 12 (蛋白名), ada12_human.
产品名称:
Human ADAM12/ Disintegrin and metalloproteinase domain-containing protein 12 CLIA Kit
解整合素样金属蛋白酶12
货号:
U14640h
商标:
EIAab®
监管等级:
别名:
Meltrin-alpha, UNQ346/PRO545, ADAM 12, MLTN
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Disintegrin and metalloproteinase domain-containing protein 12
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with alpha-actinin-2 and with syndecans (By similarity). Interacts with SH3PXD2A. Interacts with FST3. Interacts with RACK1; the interaction is required for PKC-dependent translocation of ADAM12 to the cell membrane.
功能:
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
亚细胞位置:
Isoform 4
Secreted
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