首页 > 重组蛋白 > Human ZNF335 Recombinant Protein

ZNF335 (基因名), Zinc finger protein 335 (蛋白名), zn335_human.

产品名称:

Human ZNF335/ Zinc finger protein 335 Recombinant Protein
锌指蛋白335

货号:

R1019h

商标:

EIAab^®

监管等级:

RUO

别名:

NRC-interacting factor 1, NIF-1

序列号:

Q9H4Z2

来源:

E.coli

种属:

Human

标签:

His

序列:

Recombinant protein

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

Epigenetics

规格 & 价格:

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Human ZNF335 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献 ( 1 )
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 20q13.12 by HGNC 20q13.12 by Entrez Gene 20q13.12 by Ensembl

ZNF335 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Interacts with NCOA6; may enhance ligand-dependent transcriptional activation by nuclear hormone receptors. Interacts with CNOT6. Interacts with RQCD1; the interaction is direct. Interacts with members of histone H3'Lys4'(H3K4) methyltransferase complexes ASCL2, CXXC1, KMT2A/MLL1, RBBP5, SETD1A and WDR5. Part of a complex composed at least of ASCL2, EMSY, HCFC1, HSPA8, CCAR2, MATR3, MKI67, RBBP5, TUBB2A, WDR5 and ZNF335; this complex may have a histone H3-specific methyltransferase activity.

功能:

Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhances ligand-dependent transcriptional activation by nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST. Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation.

亚细胞位置:

Nucleus

数据库链接

UniGene:

Hs.174193

SMR:

Q9H4Z2

STRING:

9606.ENSP00000325326

KEGG:

hsa:63925

MIM:

610827

Uniprot:

Q9H4Z2

相关产品

Mouse Znf335 ELISA Kit

Rat Znf335 ELISA Kit

Mouse Znf335 CLIA Kit

Rat Znf335 CLIA Kit

Mouse Znf335 Protein

序列长度:

1342

序列:

仅供参考，详细请咨询（services@eiaab.com）

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1342:

AVADAAMAQA | QGLFGTDETV | PEHIQQLQHQ | GIEYDVITLA | DD

3D 模型:

3D 结构:

免疫原序列:

验证序列:

[1].

"Analytical Performance of ELISA Assays in Urine: One More Bottleneck towards Biomarker Validation and Clinical Implementation"

Chatziharalambous D, Lygirou V, Latosinska A, et al

From: PloS one

[1].

"Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation."

(PMID: 19131338)

[2].

"NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC."

(PMID: 12215545)

[3].

"Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1."

(PMID: 18180299)

[4].

"Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation."

(PMID: 23178126)

[5].

"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

(PMID: 20379614)

[6].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."

(PMID: 14702039)

[7].

"The DNA sequence and comparative analysis of human chromosome 20."

(PMID: 11780052)

[8].

"Architecture of the human interactome defines protein communities and disease networks."

(PMID: 28514442)

[9].

"Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation."

(PMID: 28112733)

[10].

"Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci."

(PMID: 25920553)

[1].

人锌指蛋白335(ZNF335)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人锌指蛋白335(ZNF335)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人锌指蛋白335(ZNF335)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人锌指蛋白335(ZNF335)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人锌指蛋白335(ZNF335)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人锌指蛋白335(ZNF335)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人锌指蛋白335(ZNF335)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人锌指蛋白335(ZNF335)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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