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首页  >  重组蛋白  >  Mouse Zfhx3 Recombinant Protein
Zfhx3 (基因名), Zinc finger homeobox protein 3 (蛋白名), zfhx3_mouse.
产品名称:

Mouse Zfhx3/ Zinc finger homeobox protein 3 Recombinant Protein
锌指同源盒蛋白

货号:

R1065m

商标:
EIAab®
监管等级:
别名:

AT motif-binding factor 1, AT-binding transcription factor 1, Alpha-fetoprotein enhancer-binding protein, Zinc finger homeodomain protein 3, ZFH-3, Atbf1

序列号:
Q61329
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Zfhx3 Protein
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Mouse Zfhx3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with ALKBH4 and PIAS3 (By similarity). Interacts with FNBP3. Interacts with ESR1, RUNX3, TRIM25, SMAD2 and SMAD3.


功能:
Transcriptional regulator which can act as an activator or a repressor. Inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. In concert with SMAD-dependent TGF-beta signaling can repress the transcription of AFP via its interaction with SMAD2/3 (By similarity). Regulates the circadian locomotor rhythms via transcriptional activation of neuropeptidergic genes which are essential for intercellular synchrony and rhythm amplitude in the suprachiasmatic nucleus (SCN) of the brain (PubMed:26232227). Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer. In association with RUNX3, upregulates CDKN1A promoter activity following TGF-beta stimulation.


亚细胞位置:
Nucleus Cytoplasm Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. Expressed in nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body.


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