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Zeb1 (基因名), Zinc finger E-box-binding homeobox 1 (蛋白名), zeb1_mouse.
产品名称:

Mouse Zeb1/ Zinc finger E-box-binding homeobox 1 Recombinant Protein
ZEB1

货号:

R14970m

商标:
EIAab®
监管等级:
别名:

Delta EF1, Transcription factor 8, Zinc finger homeobox protein 1a, TCF-8, MEB1, Tcf8, Zfhx1a, Zfx1a, Zfx1ha

序列号:
Q64318
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Zeb1 Protein
规格 & 价格: cart
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Mouse Zeb1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts (via N-terminus) with SMARCA4/BRG1.


功能:
Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1 (By similarity). Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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