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Zbtb1 (基因名), Zinc finger and BTB domain-containing protein 1 (蛋白名), zbtb1_mouse.
产品名称:

Mouse Zbtb1/ Zinc finger and BTB domain-containing protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
序列号:
Q91VL9
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Zbtb1 Protein
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Mouse Zbtb1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer (By similarity). Homodimer (PubMed:22753936). Interacts (via BTB domain) with TRIM28 (unphosphorylated or phosphorylated form).


功能:
Acts as a transcriptional repressor (By similarity). Represses cAMP-responsive element (CRE)-mediated transcriptional activation (By similarity). In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (By similarity). Plays a key role in the transcriptional regulation of T lymphocyte development (PubMed:22201126, PubMed:22753936).


亚细胞位置:
Nucleus Nucleus Nucleoplasm Localized in dot-like structures in the nucleus. Colocalized with SMRT in nuclear bodies. The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies (By similarity).


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