EIAab
首页  >  重组蛋白  >  Human ZBTB1 Recombinant Protein
ZBTB1 (基因名), Zinc finger and BTB domain-containing protein 1 (蛋白名), zbtb1_human.
产品名称:

Human ZBTB1/ Zinc finger and BTB domain-containing protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

KIAA0997

序列号:
Q9Y2K1
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ZBTB1 Protein
×
Human ZBTB1 Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 14q23.3 by HGNC 14q23.3 by Entrez Gene 14q23.3 by Ensembl
ZBTB1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. Homooligomer. Isoform 1 and isoform 2 can homodimerize. Heterodimer of isoform 1 and isoform 2. Interacts (via BTB domain) with TRIM28 (unphosphorylated or phosphorylated form) (PubMed:24657165).


功能:
Acts as a transcriptional repressor (PubMed:20797634). Represses cAMP-responsive element (CRE)-mediated transcriptional activation (PubMed:21706167). In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (PubMed:24657165). Plays a key role in the transcriptional regulation of T lymphocyte development.


亚细胞位置:
Nucleus Nucleus Nucleoplasm Localized in dot-like structures in the nucleus (PubMed:21706167). Colocalized with SMRT in nuclear bodies (PubMed:20797634). The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies(PubMed:20797634).


该产品尚未在任何出版物中被引用。

[1].
"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[2].
"Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis."

[3].
"Transcription factor zinc finger and BTB domain 1 is essential for lymphocyte development."

[4].
"Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE."

[5].
"Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif."

[6].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[7].
"Architecture of the human interactome defines protein communities and disease networks."

[8].
"Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation."

[9].
"Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing."

[10].
"Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com