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ZBTB7A (基因名), Zinc finger and BTB domain-containing protein 7A (蛋白名), zbt7a_human.
产品名称:

Human ZBTB7A/ Zinc finger and BTB domain-containing protein 7A Recombinant Protein

货号:

R2962h

商标:
EIAab®
监管等级:
别名:

Factor binding IST protein 1, Factor that binds to inducer of short transcripts protein 1, HIV-1 1st-binding protein 1, Leukemia/lymphoma-related factor, POZ and Krueppel erythroid myeloid ontogenic factor, TTF-I-interacting peptide 21, Zinc finger protein 857A, FBI-1, POK erythroid myeloid ontogenic factor, TIP21, FBI1, LRF, ZBTB7, ZNF857A

序列号:
O95365
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ZBTB7A Protein
规格 & 价格: cart
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Human ZBTB7A Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 19p13.3 by HGNC 19p13.3 by Entrez Gene 19p13.3 by Ensembl
ZBTB7A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with BCL6.


功能:
Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"FBI-1, a factor that binds to the HIV-1 inducer of short transcripts (IST), is a POZ domain protein."

[2].
"Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator."

[3].
"Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene."

[4].
"Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors."

[5].
"Somatic human ZBTB7A zinc finger mutations promote cancer progression."

[6].
"Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin."

[7].
"Pokemon (FBI-1) interacts with Smad4 to repress TGF-β-induced transcriptional responses."

[8].
"LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair."

[9].
"The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis."

[10].
"FBI-1 functions as a novel AR co-repressor in prostate cancer cells."
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