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YTHDF1 (基因名), YTH domain-containing family protein 1 (蛋白名), ythd1_human.
产品名称:

Human YTHDF1/ YTH domain-containing family protein 1 Recombinant Protein

货号:

R8037h

商标:
EIAab®
监管等级:
别名:

Dermatomyositis associated with cancer putative autoantigen 1, DACA-1, C20orf21

序列号:
Q9BYJ9
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Epigenetics
Human YTHDF1 Protein
规格 & 价格: cart
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Human YTHDF1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 20q13.33 by HGNC 20q13.33 by Entrez Gene 20q13.33 by Ensembl
YTHDF1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with ribosomes. Interacts with eIF3 (EIF3A or EIF3B).


功能:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440).


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"N6-methyladenosine-dependent regulation of messenger RNA stability."

[2].
"YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA."

[3].
"N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency."

[4].
"Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins."

[5].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[6].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[7].
"The DNA sequence and comparative analysis of human chromosome 20."

[8].
"Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells."

[9].
"The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation."

[10].
"Overexpression of YTHDF1 is associated with poor prognosis in patients with hepatocellular carcinoma."
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