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YAF2 (基因名), YY1-associated factor 2 (蛋白名), yaf2_human.
产品名称:

Human YAF2/ YY1-associated factor 2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
序列号:
Q8IY57
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human YAF2 Protein
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Human YAF2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 12q12 by HGNC 12q12 by Entrez Gene 12q12 by Ensembl
YAF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with MYC, MYCN, RNF2/RING1B and YY1. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2.


功能:
Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1."

[2].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[3].
"Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling."

[4].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[5].
"Yaf2 inhibits Myc biological function."

[6].
"A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells."

[7].
"Functional interaction of Yaf2 with the central region of MycN."

[8].
"Architecture of the human interactome defines protein communities and disease networks."

[9].
"Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis."

[10].
"EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis."
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