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XYLT1 (基因名), Xylosyltransferase 1 (蛋白名), xylt1_human.
产品名称:

Human XYLT1/ Xylosyltransferase 1 Recombinant Protein
Human木糖转移酶-1

货号:

R11585h

商标:
EIAab®
监管等级:
别名:

Peptide O-xylosyltransferase 1, Xylosyltransferase I, XT-I, XT1

序列号:
Q86Y38
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human XYLT1 Protein
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Human XYLT1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 16p12.3 by HGNC 16p12.3 by Entrez Gene 16p12.3 by Ensembl
XYLT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer.


功能:
Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass type II membrane protein Golgi apparatus membrane Single-pass type II membrane protein Secreted Some fraction is also found in the extracellular space together with chondroitin sulfate proteoglycans, suggesting that it can be secreted.


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II."

[2].
"The missing "link": an autosomal recessive short stature syndrome caused by a hypofunctional XYLT1 mutation."

[3].
"The xylosyltransferase Iota gene polymorphism c.343G>T (p.A115S) is associated with decreased serum glycosaminoglycan levels."

[4].
"Xylosyltransferase gene variants and their role in essential hypertension."

[5].
"Xylosyltransferase I variants and their impact on abdominal aortic aneurysms."
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