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WNT10B (基因名), Protein Wnt-10b (蛋白名), wn10b_human.
产品名称:

Human WNT10B/ Protein Wnt-10b Recombinant Protein
蛋白质Wnt-10b

货号:

R5410h

商标:
EIAab®
监管等级:
别名:

Protein Wnt-12, WNT12

序列号:
O00744
来源:
E.coli
种属:
Human
标签:
His
序列:
29-389aa
预估分子量:
39.71 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Stem Cells
Human WNT10B Protein
规格 & 价格: cart
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Human WNT10B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 12q13.12 by HGNC 12q13.12 by Entrez Gene 12q13.12 by Ensembl
WNT10B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin.


亚细胞位置:
Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas."

[2].
"Homozygous WNT10b mutation and complex inheritance in Split-Hand/Foot Malformation."

[3].
"Proto-oncogene WNT10B is up-regulated by tumor necrosis factor alpha in human gastric cancer cell line MKN45."

[4].
"Isolation, characterization and chromosomal localization of human WNT10B."

[5].
"Mutations in WNT10B Are Identified in Individuals with Oligodontia."

[6].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[7].
"Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"."

[8].
"High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men."

[9].
"Polymorphisms of the WNT10B gene, bone mineral density, and fractures in postmenopausal women."

[10].
"Association analysis of WNT10B with bone mass and structure among individuals of African ancestry."
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