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Vegfa (基因名), Vascular endothelial growth factor A (蛋白名), vegfa_mouse.
产品名称:

Mouse Vegfa/ Vascular endothelial growth factor A Recombinant Protein
血管内皮生长因子A

货号:

R0143m

商标:
EIAab®
监管等级:
别名:

Vascular permeability factor, VPF, VEGF-A, Vegf

序列号:
Q00731
来源:
E.coli
种属:
Mouse
标签:
His
序列:
27-190aa
预估分子量:
18.04 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
  • Mouse Vegfa Protein
  • Mouse Vegfa Protein
  • Mouse Vegfa Protein
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Mouse Vegfa Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
Mouse Vegfa Protein
The PCR product of mouse Vegfa gene was determined by 1% Agarose stained with EB.
Mouse Vegfa Protein
Recombinant mouse Vegfa protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Homodimer; disulfide-linked. Also found as heterodimer with PGF (By similarity). Interacts with NRP1 (PubMed:26503042).


功能:
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (PubMed:26503042).


亚细胞位置:
Isoform VEGF-3 Cell membrane Peripheral membrane protein Remains cell-surface associated unless released by heparin.


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